T-Array®
Genetic test that identifies copy number changes in the genome
TISMOO’s T-Array® is a postnatal genetic test that identifies copy number changes in the genome. It allows the detection of chromosomal alterations that previously were within methodological error. It is also possible to identify gains and losses of a single gene by the association of resolution and the large number of SNP (Single Nucleotide Polymorphism) covered by the chip.
Furthermore, with the T-Array® it is possible to identify regions of absence of heterozygosity, and its findings may help in the diagnosis of developmental disorders.
1. Prepare for your appointment
In order to carry out the T-Array, in addition to the medical request for the examination to be carried out with the desired quality, we will ask you to fill in a pre-registration with a clinical questionnaire (the documents can be filled in digitally or at the time of the consultation – to be combined with the Tismoo team).
Prepare
Pre-Exam – The collection must be carried out by saliva. It is necessary to fast for 30 minutes, including water. Watch the instructions.
Sample types
The test is performed using saliva samples from the patient and, when requested, will also be collected from parents.
Collect
The collection can be carried out at your home using an exclusive Tismoo kit, which is sent by post to your address, and following the standard procedure recommended by Tismoo for collecting and sending the sample (watch the video).
Necessary documents
- Medical request
- Forms sent by Tismoo
Deadline
Up to 60 calendar days.
The deadline for delivery of the report is counted from the receipt of the sample by the Tismoo team.
Related diseases
The test can be used to diagnose genetic health conditions of unknown origin or caused by one of hundreds of genes, such as developmental disorders, syndromes in general, in addition to Autism Spectrum Disorder.
Genes analyzed
Capture of 4800 mapped genes. 300,000 probes across the entire genome. Coverage of ~89% of the 1,297 genes cured by Clingen (an institute formed to define clinically relevant genes and variants) with at least 3 probes per exon.
Technical information
The T-Array® is the analysis of Copy Number Variation (CNVs), as losses (microdeletions) and gains (microduplications) of DNA, using the Affymetrix Cytoscan platform – 750K. It has a resolution of 100 Kpb for genomic gains and losses and regions of homozygosity reported when an LCSH is greater than 5 Mb. The test is able to identify regions of absence of heterozygosity. These findings may aid in the diagnosis of developmental disorders.
Quero fazer o exame!
Alameda Santos, 200 – cj.903 – Paraíso
São Paulo | SP | Brasil
CEP 01418-000
+55 (11) 93761-0013
+55 (11) 3587-1273
